Stomatocyte in Stomatocyte: A New Shape of Polymersome Induced via Chemical-Addition Methodology
نویسندگان
چکیده
منابع مشابه
Biodegradable Hybrid Stomatocyte Nanomotors for Drug Delivery
We report the self-assembly of a biodegradable platinum nanoparticle-loaded stomatocyte nanomotor containing both PEG-b-PCL and PEG-b-PS as a potential candidate for anticancer drug delivery. Well-defined stomatocyte structures could be formed even after incorporation of 50% PEG-b-PCL polymer. Demixing of the two polymers was expected at high percentage of semicrystalline poly(ε-caprolactone) (...
متن کاملRed cell rheology in stomatocyte-echinocyte transformation: roles of cell geometry and cell shape.
The influence of the shape of the red blood cell during stomatocyte-echinocyte transformation on its deformability was studied by microsieving through pores with diameters of 2.6, 4.5, and 6.9 micron. A stomatocytic transformation was produced by chlorpromazine (0.02, 0.1, and 0.5 mmol/L) and an echinocytic transformation by sodium salicylate (7.5, 30, and 120 mmol/L). For spherostomatocytes, a...
متن کاملThe discocyte-stomatocyte equilibrium of normal and pathologic red cells.
By R. I. Weed and M. Bessis T HE DISCOCYTE-ECHINOCYTE transformation has become well known through the studies of Jolly,’ Ponder,2 Teitel-Bernard,3 Furchgott and Ponder,4 and, more recently, by Weed et al.5 and Bessis and Lessin.68 This subject has been recently reviewed in this journal by Brecher and Bessis.9 Certam characteristics of this transformation have been established. Intrinsic factor...
متن کاملRedox‐Sensitive Stomatocyte Nanomotors: Destruction and Drug Release in the Presence of Glutathione
The development of artificial nanomotor systems that are stimuli-responsive is still posing many challenges. Herein, we demonstrate the self-assembly of a redox-responsive stomatocyte nanomotor system, which can be used for triggered drug release under biological reducing conditions. The redox sensitivity was introduced by incorporating a disulfide bridge between the hydrophilic poly(ethylene g...
متن کاملOn the mechanism of stomatocyte-echinocyte transformations of red blood cells: experiment and theoretical model.
This study represents an attempt to achieve a better understanding of the stomatocyte-echinocyte transition in the shape of red blood cells. We determined experimentally the index of cell shape at various ionic strengths and osmolarities for native and trypsin-treated human erythrocytes. For every given composition of the outer phase, we calculated the ionic strength in the cells and the transm...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nano Letters
سال: 2018
ISSN: 1530-6984,1530-6992
DOI: 10.1021/acs.nanolett.8b00187